To explore the inhibitory effect of eae and molecular mechanism on hepatocellular carcinoma hcc smmc. Compounds 110 were isolated and purified by silica gel, sephadex lh20 and rp18 chromatogarphy. Plants profile for euphorbia helioscopia madwomans milk. Show all show tabs madwomans milk general information. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. Once used as a treatment for warts from the plants milky sap, which is poisonous. It is a herbaceous annual plant, native to most of europe, northern africa, and eastward through most of asia folk names include wart spurge, umbrella milkweed and madwomans milk. Find, read and cite all the research you need on researchgate. Euphorbia helioscopia euforbia calenzuola flora italiana. This file contains additional information such as exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. The sap contains a latex which is toxic on ingestion and highly irritant externally, causing photosensitive skin reactions and severe inflammation, especially on contact with eyes or open cuts. Euphorbia helioscopia name synonyms euphorbion helioscopium l. Seventeen new jatrophane diterpenoid esters, helioscopianoids aq 1 17, were isolated from the whole plants of euphorbia helioscopia. Weed description a winter annual that grows prostrate along the ground with tips and upper stem portions ascending decumbent growth habit.
Occurrence sun spurge is an annual weed of cultivated fields on sandy and clay loams long, 1938. Euphorbia helioscopia describiose por carlos linneo y espublizose en species plantarum 1. The present study aimed to standardize the crude drug from euphorbia helioscopia by doing qualitative and quantitative analysis of different pulverized plant parts and extracts. Provides authoritative information on the flora of western australia. The bioactive substance investigation of euphorbia ebracteolata obtained 17 compounds by various chromatographic techniques. Files are available under licenses specified on their description page.
This species is poisonous to humans and livestock and its milky sap. Cytotoxic macrocyclic diterpenoids from euphorbia helioscopia. Euphorbia is sometimes used in ordinary english to collectively refer to all members of euphorbiaceae in deference to the type genus, not just to members of the genus. Usda, ars, germplasm resources information network. Blood sampling was done by cardiac puncture after 14 days from each group for biochemical. Pollination study of euphorbia helioscopia euphorbiaceae. Is folklore use of euphorbia helioscopia devoid of toxic. The etoh extracts of the whole plants of euphorbia helioscopia afforded 17 new jatrophane diterpenoid esters, helioscopianoids aq 1 17, along with eight known compounds 1825. Large image for euphorbia helioscopia madwomans milk. A study was planned to count into the antimicrobial activity and phytochemical screening of euphorbia helioscopia. Physicochemical analysis determination of moisture contents, total ash, water insoluble ash, sulphated ash, acid insoluble ash, and water and alcohol extractives.
Compounds 8 and 16 showed pglycoprotein inhibitory activities, and compounds 2, 8, and 12 showed neuroprotective activities. This page was last edited on 6 september 2017, at 21. But the effect of eae for tumor cells in vivo has not been reported. Amygdaloides latex, asthma spurge, balsam spurge, bisabolane sesquiterpenoid, caper spurge, christmas flower, dieterpenoids segetanes, jatrophanes, paralianes. Euphorbia helioscopia, the sun spurge, is a species of flowering plant in the spurge family euphorbiaceae. Department of agriculture agricultural research service. Chemical constituents and biological activities article pdf available january 2012 with 2,010 reads. Sun spurge, euphorbia helioscopia flowers naturegate. Beginning the citological and histoanatomical study of the euphorbia species from the romanian flora, we have published a contribution 7, 8, 9 and three others are in press. Materials and methods plant collection the fresh plant specimens of euphorbia helioscopia l. The record derives from wcsp data supplied on 20120323 which reports it as an accepted name record 80043 with original publication details. Helioscopianoids aq, bioactive jatrophane diterpenoid esters. Sun spurge is common throughout the uk especially in lowland areas. Sun spurge, euphorbia helioscopia, poisonous plants.
The organization for economic cooperation and development oecd for chemical testing guidelines no. Euphorbia helioscopia little guid, chirkie, wartiegirse, kirn staff, cats milk, wratwirt, wratweed, milkwirt is a species o flouerin plant in the spurge faimily euphorbiaceae. Euphorbia helioscopia in the germplasm resources information network grin, u. In an early survey of norfolk and bedfordshire it was. To download the original size of this image, click on the. Euphorbia helioscopia madwomans milk pfaf plant database. It belongs to the plant family euphorbiaceae and genus euphorbia. However, the leaves of cypress spurge are much more linear than those of sun spurge and upon closer examination distinguishing between the two species is relatively easy.
The toxicity can remain high even in dried plant material. Anjum3 1university college of pharmacy, university of the punjab, 2faculty of pharmacy, the university of lahore. Euphorbia helioscopia wikipedia, a enciclopedia livre. The results can also be downloaded as a csv file unicode utf8 encoding see status, confidence level, source for definitions. Sun spurge is a somewhat rare weed of pastures, hayfields, and winter small grains in. 154751 january 2009 with 173 reads how we measure reads. Some euphorbias are commercially widely available, such as poinsettias at christmas. Cytotoxic macrocyclic diterpenoids from euphorbia helioscopia article pdf available in archives of pharmacal research 3112. Groups ii and iii were administered methanol extract of e. It is common in cultivated land and waste places throughout the uk especially lowland areas clapham et al. General information about euphorbia helioscopia ephhe. If you know of control methods for euphorbia helioscopia, please let us know. Secoheliosphanes a and b and secoheliospholane a, three. It is a herbaceous annual plant, native to most of europe, northern africa, and eastward through most of asia.
It has been reported that euphorbia helioscopia has antitussive properties and might be useful in patients with chronic bronchitis 12 the exact mechanism of action is not known. The plants former finnish name refers to the way its latex was used to treat dry, flaky eczema that was caused by parasitic fungi. Sun spurge is an annual weed of cultivated fields and waste places on sandy and clay loams. Folk names include wart spurge, umbrella milkweed and madwomans milk. All structured data from the file and property namespaces is.
It is a yerbaceous annual plant, native tae maist o europe, northren africae, an eastwart throu maist o asie. Physicochemical and phytochemical analysis of euphorbia. A large image of euphorbia helioscopia madwomans milk from the usda plants database. The distribution in this summary table is based on all the information available.
When several references are cited, they may give conflicting information on the status. Each plant profile in the database contains nomenclature info, botanical data, plant description, large, highresolution pictures, images and photos of the plants and its parts, detailed. In addition, users can learn about the location of vouchered specimens and see images to get a better visual for each plant. Sun spurge euphorbia helioscopia is regarded as an environmental weed in western australia. It is most common as a weed of cultivated areas, but also invades natural habitats and occasionally even conservation areas e. To evaluate acute toxic effects of euphorbia helioscopia in order to assure the safety and usefulness of herbal remedy. Hepatocellular carcinoma growth is inhibited by euphorbia.
Diterpenes inhibiting no production from euphorbia helioscopia. Sun spurge, euphorbia helioscopia, poisonous plants illustrations b6aj6n from alamys library of millions of high resolution stock photos, illustrations and vectors. All structured data from the file and property namespaces is available under the creative commons cc0 license. Lathyrane diterpenes from euphorbia prolifera and their inhibitory activities on lpsinduced no production sesquiterpenes and diterpenes from euphorbia thymifolia diterpenes and phloracetophenones from euphorbia portulacoides. Euphorbia euphorbia sp plant profiler sigmaaldrich. It is a yerbaceous annual plant, native tae maist o europe, northren africae, an eastwart throu maist o asie references. Their structures were elucidated mainly by spectroscopic methods. You may do so in any reasonable manner, but not in.
Pdf antimicrobial activity and phytochemical screening. Euforbia calenzuola dipartimento di scienze della vita, universita di trieste progetto dryades picture by andrea moro comune di sgonico, campo coltivato ai margini dellabitato. Brief description grazyna paczkowska, thursday 29 august 1996. Despite of significant numbers of insect visitors in euphorbia species being reported, e. Ten known compounds, helioscopinolide a1, helioscopinolide b2, scopoletin3, scoparone4, isoscopoletin5, licochalone. This plant is often found in the wild in northern europe. This file is licensed under the creative commons attributionshare alike 3. Euphorbia is a very large and diverse genus of flowering plants, commonly called spurge, in the spurge family euphorbiaceae. Euphorbia helioscopia belongs to euphorbiaceae family which contains 8000 species.
Euphorbia helioscopia ephheoverview eppo global database. The results can also be downloaded as a csv file unicode utf8 encoding. Their structures were elucidated by extensive spectroscopic methods and mo 2 oac 4induced ecd analysis, and the structures of compounds 1, 2, and 7 were confirmed by xray crystallography. Diterpenes from euphorbia paralias diterpenes from euphorbia peplus two diterpenes from euphorbia sieboldiana. The new york flora atlas is a source of information for the distribution of plants within the state, as well as information on plant habitats, associated ecological communities, and taxonomy. It is used in the treatment of various ailments like warts cure, skin diseases, intestinal parasites, migraine, gonorrhea. Sun spurge is one of the more common of the small amount of genus euphorbia species that grow in finland. Physicochemical and phytochemical analysis of euphorbia helioscopia l. From a distance, this plant might be confused with cypress spurge euphorbia cyparissias, which has very similar flowers. The plant is probably toxic to stock, but being unpalatable is seldom, if ever, eaten in quantities which cause poisoning. Helioscopianoids aq, bioactive jatrophane diterpenoid. To study the chemical constituents of euphorbia helioscopia. Secoheliosphanes a 1 and b 2 and secoheliospholane a 3, possessing an unusual 7,8secojatrophane skeleton and an unprecedented 9,10seco7,10epoxyjatropholane skeleton, respectively, were isolated from the whole plants of euphorbia helioscopia, along with two biogenetically precursors, a new jatrophane diterpene, 2epieuphornin i 4 and a known jatrophane diterpene, euphoscopin a 5. The species is hermaphrodite has both male and female organs and is pollinated by flies.
This is the profile for the plant euphorbia helioscopia sun spurge tenghud raddiena. It has been investigated euphorbia species until now. Is folklore use of euphorbia helioscopia devoid of toxic effects. Stems single or with ascending branches from near base, 357 mm thick, sometimes slightly fistulose, smooth and glabrous.
974 437 1135 1479 1425 309 792 1075 1519 127 1288 851 1215 459 1525 161 764 378 1216 708 956 772 1007 51 382 160 941 1516 1007 1444 1434 1380 688 524 1387 1473 798 1188 820 321